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Thus, phenobarbital may be more effective and better tolerated than is commonly recognized

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The peptide begins initiating healing processes at the cellular level, but these changes take time to manifest as symptomatic improvement

The ability for THC to inhibit NF-B and reduce the release of IL-1 and TNF- from microglia also extends to monocytes/macrophages and lymphocytes in human and rodent cell lines and primary cell cultures (Shivers et al., 1994

Interestingly, CB 2 R mRNA expression can vastly increase during an inflammatory insult, with microglia from mice displaying as much as a 10-fold increase (Maresz et al., 2005)