What they found: No serious adverse events triggered by AOD-9604 The most frequent side effects: headache (~5 %), occasional fatigue, at the same frequency as placebo No changes in IGF-1 levels, glycemia, blood pressure, heart rate No signals of cardiovascular, hepatic or renal toxicity Safety profile comparable to placebo Why it matters: From a safety perspective, AOD-9604 is one of the safest peptides in the clinical registry
Both are publicly searchable
The inclusion of Vitamin E helps fade acne scars and discoloration
Later, TRPM2 activator role of oxidative stress from ADPR was reported in transfected cells by single channel patch-clamp experiments (Naziroglu and Lckhoff, 2008)
The drug needs to be injected into the fatty tissue just below the skin
Its helpful to track how you feel in the days following your first shot