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Kaufman said he didnt want to sound hyperbolic about the new drugs, but then sounded pretty hyperbolic when he described his short, but so far positive, experience with them in these diseases as eye-opening and incredible

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Wegovy carries FDA approval for chronic weight management in adults with a BMI 30, or 27 with at least one weight-related comorbidity (hypertension, dyslipidemia, type 2 diabetes, sleep apnea)

The efficacy and safety of tirzepatide, with a special focus on cardiovascular safety, were investigated in the 52-week SURPASS-4 trial testing tirzepatide versus insulin glargine in adults with T2D and a high cardiovascular risk under inadequate glycemic control at baseline on one to three oral glucose-lowering medications (metformin, sulfonylurea, SGLT-2 inhibitor) (74)

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