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Pharmaceutical companies are actively developing new formulations and analogs that could offer similar or improved benefits without the need for injections

Cardiovascular safety trial demonstrating that the DPP-4 inhibitor sitagliptin does not increase MACE or hospitalization for heart failure in patients with T2DM and high cardiovascular risk

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Mechanistically, UDCA activates K_ATP channels to hyperpolarize myofibroblast membrane potential, counteracting TC-induced depolarization

Oxidative Medicine and Cellular Longevity 876834

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