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Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates
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The angiogenic effect is not direct on isolated cells in culture but appears in vivo when blood vessels and surrounding tissue are present (Brcic et al., 2009)
Another advantage is that Ipamorelin does not suppress the bodys own feedback loop or downregulate natural GH production , even with long-term use
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