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Pathophysiologic functions of enzymes In case of head and neck cancers, GPX1 allelic loss has been shown to occur in histopathologically normal tissue adjacent to tumors, indicating that loss at this locus may be an early event in cancer evolution

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162 During breast cancer chemotherapy, specific tumor cells exhibit upregulation of SASP genes, accompanied by an augmented expression of immunosuppressive molecules PD-L1 and CD80 within these tumor cells

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