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Compared to SGLT2i, the GLP-1RA/SGLT2i combination was associated with greater reduction in HbA1c (0.74%), body weight (1.61 kg), and systolic blood pressure (3.32 mmHg)

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The field shows growing interest in novel delivery systems, including liposomal formulations, sublingual preparations, and buccal absorption methods, attempting to overcome the documented challenges of glutathiones poor gastrointestinal bioavailability