Safety and efficacy of liraglutide on reducing visceral and ectopic fat in adults with or without type 2 diabetes mellitus: A systematic review and meta-analysis
REDEFINE 1 adults with overweight/obesity, no diabetes GI adverse events were reported in 79.6% of CagriSema participants vs 39.9% on placebo
GLP-1 receptor agonists (GLP-1 RAs) have transformed obesity and Type 2 diabetes mellitus (T2DM) management, offering benefits in glucose regulation, weight loss, and cardiometabolic health (6)
EClinicalMedicine 58 , 101882 (2023)
Comparative effects of the antioxidant glutathione with metformin and Diane-35 on hormonal, metabolic, and inflammatory indicators in a DHEA-induced PCOS rat model
Early phase 2 data for retatrutide, published in the New England Journal of Medicine in 2023, showed weight loss of up to about 24% over 48 weeks, with additional improvements in fasting glucose and insulin sensitivity