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10.3390/ijms20112723 76 ManciasJ

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Interestingly, the treatment demonstrated dose-dependent therapeutic effects, with moderate dosages proving more effective than high doses (1,000 mg/kg), possibly due to pharmacodynamic principles, where excessive concentrations saturate biological pathways and diminish therapeutic outcomes (Tyagi et al., 2025

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It has been reported that some domains of ACTL6A suggest that it is a member of the actin-related gene family, which is important in proteinprotein interactions 15