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[3] [4] Despite the absence of confirmed human cases directly attributable to GLP-1 therapy, the FDA requires this warning as a precautionary measure for many GLP-1 medications

These medications exert different effects on stroke, hospitalisations for heart failure, and key adverse events in different subgroups

Packer M, Zile MR, Kramer CM, Baum SJ, Litwin SE, Menon V, et al

j , Mean time to semaglutide-induced activation in AP GLP1R and NTS GLP1R neurons depicted in h (n = 5 mice, two-sided unpaired t-test, p=ns)

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