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These individual unimolecular multi-agonists activities seemed to harmonize the overall metabolic efficacy, which predominantly results from synergistic glucagon action to increase energy expenditure, GLP-1 action to reduce caloric intake and improve glucose control, and GIP action to potentiate the incretin effect and buffer against the diabetogenic effect of inherent glucagon activity
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Combining these peptides addresses wound healing from multiple angles: the structural matrix, the cellular migration to fill it, and the blood vessel development to support it
they're precision instruments
Aziz TA, Hussain SA, Mahwi TO, Ahmed ZA
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