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Molecular characterization of organelle-type Nudix hydrolases in Arabidopsis
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b-d) Validation of labeling for proteins containing hyper-reactive arginine residues (GSHR R81, RIR1 R284, and FSCN1 R217)
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To confirm that interface IV is essential for c-MET activation, we introduced Y673A mutation into HGF to disrupt this interface, and showed that HGF Y673 mutant has a great deficiency in binding to c-MET as well as promoting c-MET activation (Fig
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