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NICE guidance prioritises SGLT2 inhibitors for those with established or high risk of cardiovascular or kidney disease, with GLP-1 receptor agonists as add-on or alternative therapy where appropriate

The same rebound effect has been seen with other chronic conditions (e.g., diabetes, etc.) that the GLP1 receptor agonist may have been managing

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The policy brief argues treating obesity now for patients on Medicaid could save the state money in the long run, by avoiding future treatment for heart disease, Type 2 diabetes and other chronic conditions associated with obesity

Oncogene 41, 613621

And then the goal is to taper you off and maintain with diet and lifestyle