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Increased [ 3 H]kainic acid binding in the prefrontal cortex in schizophrenia

Increases SIRT-1 activity as a result of enhanced NAD+ salvage, leading to beneficial epigenetic and metabolic reprogramming, including increased oxidative phosphorylation (OXPHOS) and muscle stem cell activation 1-3

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AOD-9604 produces no IGF-1 elevation, potentially making it more appropriate for individuals with cancer history or elevated baseline cancer risk

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