Weight regain is the defining challenge of obesity treatment, and the pattern after stopping medication tells you more about a drug utility than the weight loss it produces while you are taking it
Is that what theyre calling this thing
GLP-1 drugs arent new (they were FDA approved 20 years ago ), so we know weekly injections are safe because we have decades of data
doi: 10.1002/2327-6924.12510
However, when silymarin was introduced to their meals, the mice didnt become obese
Singh S, Dulai PS, Zarrinpar A, Ramamoorthy S, Sandborn WJ (2017) Obesity in IBD: epidemiology, pathogenesis, disease course and treatment outcomes