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In the context of tirzepatide therapy, which strongly improves insulin sensitivity, this is unlikely to be a problem, but it is worth monitoring in individuals with diabetes or prediabetes
In: Feingold KR, Anawalt B, Blackman MR, et al., editors
These drugs bind to GLP 1 receptors on pancreatic, gastrointestinal and central nervous system cells to enhance glucose dependent insulin secretion
Persistent hyperglycemia can mediate hypoxic or ischemic injury, as well as elicit cardiomyocyte contractile dysfunction and the NF-B signaling pathway activation, thus inducing ER stress [152]
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