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These findings highlight the peptide as a promising treatment for various muscle and bone conditions (4)

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However, Treg-cell depletion in the vWAT of older mice did not affect the inflammatory status, macrophage crowning, or the TNF-, IFN-, interleukin (IL)-1, IL-6, or IL-17 serum levels [95]

Nonetheless, low IGF-1 circulating levels are also associated with reduced insulin sensitivity [207], glucose intolerance, and T2D [207, 208, 214]