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The cytoplasmic acetoacetyl-CoA can be hydrolyzed to two molecules of acetyl-CoA by the action of the cytosolic thiolase (acetyl-CoA acetyltransferase 2) encoded by the ACAT2 gene

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Local treatment of the primary tumour with the established modalities of radiotherapy and radical prostatectomy has been explored in this context, and the use of novel minimally invasive ablative therapies has been proposed

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Additionally, light physical activity after meals like a 1015 minute walk can support digestion and reduce bloating