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Buchhagen, D.L., Qiu, L

At this point, the rate of weight loss is typically 1.5 to 2.5 pounds per week for most individuals

The functions of SCFAs are involved in modulating energy metabolism, regulating immune and inflammatory responses, and inhibiting oxidative stress and mitochondrial damage, which are mainly achieved through the activation of transmembrane G protein-coupled receptors (GPRs) and the inhibition of histone acetylation (HDAC) (7)

Gastrointestinal side effects may also lead to dehydration and acute kidney injury (Wilding et al., 2021)

Consuming coffee with or after food, rather than on an empty stomach, can significantly reduce gastric irritation and nausea