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Researchers should define the main question before selecting a model: whether the study is testing cytoprotection, migration, proliferation-associated endpoints, angiogenesis, extracellular matrix remodeling, endothelial signaling, or tissue-level recovery
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Hemoterapija kontrolie rast elija tumora hemijskim putem
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This additional step of dissociation is required because effective transduction across all cells within the 3D structure is not yet feasible, making it difficult to preserve the organoids spatial organization and cell-cell interactions
Ann Thorac Surg 94(6):1802-9, 2012
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