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doi: 10.1126/sciimmunol.abm5505 214 PandayA.SahooM
Abstract CT216: phase 1 dose escalating study of 2B3-101, glutathione PEGylated liposomal doxorubicin, in patients with solid tumors and brain metastases or recurrent malignant glioma
Aberrant post-translational modifications, namely glycation and glycosylation, together with age-dependent insufficient endogenous scavengers and quality control systems, lead to cellular overload of dysfunctional proteins
Before we dive in, sign up for PricePlow's ONE Innovation Labs news alerts so that you don't miss our upcoming coverage: Subscribe to PricePlow's Newsletter and Alerts on These Topics The Master Antioxidant Challenge Glutathione is the body's most critical antioxidant defense system
Additionally, pathways related to pentose and glucuronate interconversions, and TCA cycle were also affected ( Table 3 )
2002 Mar;133(3):274-6
