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[10] The medication is primarily eliminated through proteolytic degradation

Similarly, intraperitoneal administration of 0.25 mg/kg and 0.50 mg/kg and oral administration of 2.0 mg/kg of Dihexa significantly improved performance to levels comparable with vehicle controls

It then binds to intrinsic factor (IF), a glycoprotein secreted by the parietal cells of the gastric mucosa

Urobilin, a by-product of hemoglobin breakdown, gives urine its yellow color

That matters because, unlike most peptides, a small molecule can be studied orally as well as by injection it has no peptide bonds for digestive enzymes to cleave