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The substance is safe for use in medicines according to ICH standards, and the quality is the same from one batch of production to the next
Thus, the ENS is regarded as a second brain that can directly or indirectly respond to the microbiota and its metabolites influencing cognitive functions through gut bacteria (51)
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Rapid actin polymerization upon stimulation: When migration signals received (growth factors, chemokines, electric fields at wound edges), Thymosin Beta-4 releases actin allowing explosive polymerization forming lamellipodia and filopodia driving cell migration
In the pancreas, they enhance glucose-dependent insulin secretion whilst suppressing inappropriate glucagon release, thereby improving glycaemic control without causing hypoglycaemia
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