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What does exist: dose-proportional pharmacokinetics that make the modelling reliable, documented tolerability improvements from lower starting doses in Phase 2, and community reports

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Wu TD, Brigham EP, Keet CA, Brown TT, Hansel NN, McCormack MC

Pediatr Res 38:324331 Poorthuis BJ, Jille-Vlckova T, Onkenhout W (1993) Determination of acylcarnitines in urine of patients with inborn errors of metabolism using high-performance liquid chromatography after derivatization with 4-bromophenacylbromide