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GLP-1 medications work by: Slowing gastric emptying food stays in your stomach longer, so you feel full sooner and for longer Signaling fullness centers in the brain, reducing appetite at a neurological level Reducing cravings for high-calorie, ultra-processed foods Decreasing impulsive eating behaviors Many patients describe this as feeling satisfied with smaller portions for the first time not because they're white-knuckling a diet, but because the biological drive to overeat is turned down

Theyre easier to interpret, easier to control, and usually better for mechanism-first work

Theory of Sensitivity in Dynamic Systems , chap

Hyman agrees: Metabolic disease is the single biggest threat to human health and prosperity in the modern world, and is largely preventable

But consumers should be wary of added ingredients like sugar or sodium

Nausea, mild diarrhea, or constipation are the most common complaints