The SELECT trial [3] (N=17,604, NEJM 2023) demonstrated that these effects extend beyond weight loss to 20% cardiovascular risk reduction over 4 years
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obesity rate at a staggering 41.9% accounting for potentially 142,000,000 Americans, it was no surprise to see the growing demand for weight loss treatment, which ultimately led to a shortage of Ozempic and Wegovy
This binding helps keep senescent cells alive, despite accumulating damage and being no longer useful
While the branded product was voluntarily discontinued by the manufacturer for commercial reasons (not safety concerns), sermorelin continues to be widely prescribed through compounding pharmacies for off-label therapeutic applications (3)