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In brief, the xenografts from the Balb/c mice were embedded by paraffin and made tissue sections to carry out ki-67 (#GB111141, Servicebio, 1:500), -H2A.X (#9718, Cell Signaling Technology), cle-caspase3 (#9664, Cell Signaling Technology,1:2000), CD3 (#GB11064-100, Servicebio, 1:500), CD8 (#GB13429, Servicebio, 1:400)