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However, these treatments often rely on enema or oral administration, which generally suffers from limited rectal retention time, insufficient local drug exposure, or low systemic bioavailability, thus limiting efficacy stability and patient compliance [7, 9]
10 Preserving complex I activity with NDI1 mitigates metabolic and adipose dysfunction in Bmal1-KO mice, related to Fig
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Including improved liver indicators and decreased insulin resistance
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Tirzepatide weight loss treatment works by activating both GLP-1 and GIP receptors, helping to control cravings, slow digestion, and improve insulin sensitivity
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