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To achieve this, ES cells have higher antioxidant defense mechanisms, resulting in a lower mutational frequency than differentiated cells [119, 120]

Cp2D adenylated suc-l-Trp and suc-l-Tyr more efficiently compared to Cp1D, in agreement with the preference for aromatic amino acids displayed by Cp2B over Cp1B

Significant group differences in the GPx activity were assessed using the chi-square test and the independent-samples median test, whereas for GSH and the GSH:GSSG ratio, the t-test for independent samples and analysis of variance (ANOVA) were used

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Cells depend on antioxidant enzymes such as glutathione peroxidase (GPx) to prevent their accumulation

doi:10.1007/s00394-020-02233-0