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These two domains are adjacent to each other on the enzyme, and together form the active site of the GST where the redox reaction occurs

It has demonstrated that Fer-1 can effectively inhibit the oxidation of cell membranes and possess a notable protective effect on AKI (Skouta et al., 2014)

10.1016/j.ejpb.2017.03.025 Eur J Pharm Biopharm