Studies show that most patients regain a significant portion of lost weight within 1 to 2 years of discontinuing semaglutide without a structured transition plan
You just have to do what feels good to you
Endocrinologists viewed their ideal patient as an individual with established cardiovascular disease or high cardiovascular risk, including those with diabetic kidney disease, who are already being treated with more than one oral medication (including either SGLT2is or GLP1-RAs) and an HbA1c level exceeding the established target
When to call your doctor immediately: Severe abdominal pain (could indicate pancreatitis or gallbladder issues) Persistent vomiting that prevents you from keeping fluids down Signs of allergic reaction (rash, difficulty breathing, swelling) Vision changes Rapid heart rate or palpitations Thoughts of self-harm (rare but documented mood changes) Can GLP-1 Medications Help With Stubborn Belly Fat
They are reported by users and observed by clinicians
Treatment with Fc-GLP-1 in mice fed a chow diet significantly increased Acta2 (encoding -SMA), Col1a1 , Tgfb and Mmp2 mRNAs (Fig