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doi: 10.1161/ATVBAHA.120.314139 171

This was accompanied by reduced TNF- and elevated IL-10, indicating suppressed inflammation and corresponding reductions in anxiety-like behavior

Users often report consuming 700-1,000 fewer calories per day, with reduced cravings for high-fat, high-sugar, and processed foods.1 Retailers like Walmart have already observed a decline in snack and sweets purchases among customers using these medications.2 The shift is quantifiable and accelerating

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Multiple systematic reviews and meta-analyses, of predominantly cohort studies, have shown that metabolic bariatric surgery is consistently associated with reduced cardiovascular morbidity and mortality among individuals with obesity (predominantly in people at high risk of CVD with some lower quality evidence demonstrating benefit in people with established disease)

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