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As may be expected, mean diabetes duration tended to be longer in patients receiving a greater number of background medications, ranging from 7.2 to 10.6 years in patients on metformin monotherapy to 8.4 to 17.3 years in patients receiving more than one background medication

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This evidence cautions against short-term use of weight management medications, emphasises the need for further research into cost effective strategies for long-term weight control, and reinforces the importance of primary prevention. In response, Dr Trevor Steward, a senior research fellow in the School of Psychological Sciences at the University of Melbourne, said the analysis confirms what many doctors have experienced in the real world, that weight often returns after patients stop their medications

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