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Irregularities may include: Cycles shorter than 21 days or longer than 35 days Missed periods (amenorrhea) Heavy or prolonged bleeding Severe PMS or PMDD symptoms Painful cramping that worsens over time Spotting between cycles While occasional changes can happen during stress or life transitions, persistent irregular cycles usually indicate hormonal imbalance that deserves attention.

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References References A synthetic analogue of -MSH used to induce melanogenesis and tanning