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While it is indeed common, that doesnt necessarily mean it is ideal

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(2004) in SOD1 G86R mice found aberrations of energy metabolism such as reduction of adiposity, increased energy expenditure and lipolysis, and examined the effects of a high fat diet that consisted of regular chow supplemented with 21% (wt/wt) butter fat and 0.15% (wt/wt) cholesterol

Obesity is associated with altered gene expression in human tastebuds

Shin J, Padmanabhan A, de Groh ED, Lee JS, Haidar S, Dahlberg S, et al

However, the incidence of gastrointestinal events, discontinuations due to adverse events, and mean increase in pulse rate were higher with orforglipron than oral semaglutide