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Geumgangsan painted by Jeong Seon in the 18th century)

This precise targeting capability allows researchers to more effectively select candidates for further functional validation and drug development

Acknowledgements We appreciate the technical support from the Research Support Center, Graduate School of Medical Sciences, Kyushu University and partial support from intramural research funds of NIDDK, NIH

Clinical trials show average weight loss of 14.9% over 68 weeks

A report by the Institute for Clinical and Economic Review (ICER) found that although weight-loss drugs provide a net health benefit compared to lifestyle modification alone, the cost of drugs like Wegovy would need to decrease substantially (44-57%) to be considered cost-effective