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The total economic burden of cardiovascular diseases is estimated at US$177.5 billion per year (GBD 2019 Diseases and Injuries Collaborators, 2020)

Rhodiola has been demonstrated to enhance BDNF levels and activate the ERK/CREB signaling pathway (12), thereby facilitating neuronal survival and promoting neurogenesis within the hippocampus

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Ultimately, the benefits of suppositories relate to their mode of delivery as well as the quality of the ingredients they contain