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GLP-1 RAs mimic this effect by enhancing glucose-dependent insulin secretion, inhibiting glucagon, delaying gastric emptying, and reducing appetite mechanisms that can improve glycemic control and support weight loss [1]
Glucagon receptor agonism: Increases energy expenditure and promotes fat oxidation, contributing to weight reduction
You cannot reliably measure visceral fat with a mirror or scale
Study 5 was a 68-week trial that enrolled 902 patients with obesity (BMI greater than or equal to 30 kg/m 2 ) or with overweight (BMI 27-29.9 kg/m 2 ) and at least one weight-related comorbid condition such as treated or untreated dyslipidemia or hypertension
The mean duration of type 2 diabetes was 4.2 years, and the mean BMI was 33 kg/m 2
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