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Inflammation causes reactive stress, which in turn depletes glutathione

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Adv Mater 36:2401094 Jiang Y, Liao H, Yan L, Jiang S, Zheng Y, Zhang X et al (2023) A metalorganic framework-incorporated hydrogel for delivery of immunomodulatory neobavaisoflavone to promote cartilage regeneration in osteoarthritis

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The high consumers of marine sources of omega 3 fatty acids with the reduced GST activity polymorphisms had at least a 64% reduction of risk compared to the low consumer counterparts, with some polymorphisms experiencing an even greater protection

Cells were analyzed by FACSCalibur (BD Biosciences) and 20 000 events were collected