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Native IGF-1 binds with high affinity to insulin-like growth factor binding proteins (IGFBPs), which sequester the peptide in circulation and substantially reduce its free bioavailable fraction

Tan IIA induced activation of the GSH system to attenuate cardiac oxidative stress and restrain the increase in serum myocardial enzymes, thus relieving the extent of myocardial damage [154, 155]

Signal Transduction Research: Applied in experimental models exploring intracellular signaling cascades and pathway analysis

Biochem Pharmacol , 52:11471154

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