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Upon activation, IRE1 catalyzes the unconventional splicing of XBP1 mRNA, generating the transcriptionally active XBP1 spliced isoform (XBP1s)

The treatment policy estimand evaluated the treatment effect among all participants, regardless of treatment discontinuation or rescue intervention, while the trial product estimand addressed the average treatment effect in all participants assuming adherence to the treatment protocol

VarinEMMulvihillEEBeaudryJLPujadasGFuchsSTantiJFet al

The room temperature stability data can help you estimate safe transit times

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