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Serious adverse effects are rare but require immediate medical attention
however, evidence from animal [134, 135] and cellular studies [136,137,138] has demonstrated that chronic IH is more likely to cause ECD than chronic persistent hypoxia
Accordingly, the participant was included in the safety analysis set but excluded from the efficacy and PK analysis sets
doi:10.1038/s41591-024-02970-5 PubMed: This substudy demonstrated that retatrutide reduced liver fat by 81-82% at the 8mg and 12mg doses over 24 weeks, providing evidence of retatrutides multi-system metabolic benefits beyond weight loss
In: Erdman JWJ, Macdonald IA, Zeisel SH, eds
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