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Experimental data shows that at the same concentration, the biological activity of IGF-1 LR3 is 3-5 times that of natural IGF-1

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Solis et al, 2010) and decreased response to various classes of cancer therapeutics (Gadgeel et al, 2020

Olsson B, Johansson M, Gabrielsson J, Bolme P (1988)

The presence of the specialized tripeptide KPV allows researchers to monitor the competitive downregulation of nuclear factor kappa B (NF-kB) and trace the inhibition of pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) within inflamed intestinal or cutaneous tissues