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Opportunities for Ingredient Companies The GLP-1 trend presents significant opportunities for ingredient and food supplement companies, particularly those producing natural GLP-1 inducers such as prebiotic fibers, berberine, resveratrol, curcumin, and ginseng

When activated by exercise, metabolic stress, or exogenous administration in a research setting, MOTS-c translocates from the mitochondria to the cell nucleus, where it directly regulates the expression of genes related to energy metabolism, oxidative stress resistance, and cellular homeostasis

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Glutamate cysteine ligase, GSH synthase, and SLC7A11 are also transcriptional targets of NRF2 (91)