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Preclinical models have included NSAID-induced gastric mucosal damage, alcohol-induced gastric injury, restraint stress-induced lesions, inflammatory bowel disease models, and intestinal barrier permeability studies in rodent systems (1)

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Photodamage, Texture, and Surface Topography Multi-week topical studies in photodamaged skin models reported improvements in laxity, clarity, and firmness metrics, with concurrent reductions in fine-line and coarse-wrinkle measures