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As it relates to our conversation and I think writ large the whole field, youre hearing a lot, a lot more about different mechanisms

Additionally, in murine models exposed to dexamethasone, it was observed that the excretion of N-methylhistidinea marker indicative of muscle protein breakdownappeared reduced to a greater extent by IGF-1 LR3, potentially threefold more than by IGF-I

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In vivo rodent models have explored tissue-specific IGF-1R engagement by comparing the biodistribution and signalling footprint of IGF-1 LR3 against the native 70-amino acid ligand

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