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The effects of combination therapy with an SGLT2i and a GLP-1ra remain unclear

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The REWIND trial suggested that dulaglutide might be effective for both primary and secondary cardiovascular prevention in individuals with T2DM (254)

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One 2022 review of studies in Frontiers in Nutrition on berberine supplementation for adults with cardiovascular disease risk found that supplementing it reduced weight and body mass index (BMI), as well as other metrics like cholesterol and blood pressure

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J Neural Transm 77: 231236

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