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Nat Rev Mol Cell Biol (2021) 22:26682

Other indicators of poor prognosis include renal insufficiency, grade 3 or worse hepatic encephalopathy, a markedly elevated prothrombin time, or a rise in prothrombin time from day three to day four

& Fried, S

DPP4i are all small molecules that inhibit the catalytic activity of the enzyme without affecting any of the other known functions of the DPP4 protein

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