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Plasma GLP-1 concentrations (pg/mL) were significantly decreased in cocaine-experienced rats versus yoked-saline controls following 21 days of self-administration (Fig 1B) and acute withdrawal (i.e., extinction day 1) (Fig 1C)

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published in the Journal of Applied Physiology confirmed that BPC-157 significantly accelerated outgrowth of Achilles tendon explants, markedly increased in vitro tendon fibroblast migration in a dose-dependent manner, and substantially increased fibroblast survival under HO-induced oxidative stress establishing a three-part cellular mechanism (outgrowth, migration, survival) that distinguishes BPC-157s tendon repair profile from direct mitogenic agents