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What these mechanisms do NOT prove: that these pathways are activated to the same degree, duration, or tissue specificity in a human taking an oral capsule with unknown systemic bioavailability

B12 is non-toxic at any dosage and does not have any negative side effects

10.1073/pnas.1000154107 Proc

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Smaller vials (10-30 mL) labeled "Sterile Water for Injection" without "Bacteriostatic" wording are still single-use products despite the small size